Bibliometrics
- ORCID ID: 0000-0002-8392-2822
- ResearcherID: A-7331-2008
- Scopus ID: 8581614700
- Google Scholar: 5QhdsWkAAAAJ
Research
- Computational biology and bioinformatics.
- Oomycete and bacterial plant pathogens.
- Systems biology of plant-pathogen interactions.
- Comparative genomics of plant pathogens.
Research interests
My research centres on plant-pathogen interactions: I aim to understand what it is about microbial plant pathogens that enables them to infect plants, and what it is is about plants that allows microbes to cause disease on them. As a computational biologist, my work involves computational and mathematical analysis of biological data, such as sequence data, transcription profiles, and networks of metabolic and regulatory processes.
Systems biology
- Plant cells contain complex systems of signalling, regulatory and metabolic networks (Pritchard and Birch, 2011) that are perturbed by invading microbes which introduce effector proteins and other molecular species into the host. Invaded plants detect molecular components of the invading pathogen and changes to their cellular networks, often responding with effective resistance. I am interested in the implications of the dynamics and structure of cellular networks for the development of plant disease caused by microbial pathogens.
Genomics and comparative genomics of plant pathogens
- Sequenced genomes provide an opportunity for comparative genomics to determine which features might confer particular functions and behaviours on an organism. Sequence annotation also remains a challenge, even for well-studied organisms. I use computational and machine-learning approaches to aid classification of genome features and identify features that may be associated with the ability of a microbe to cause disease.
Phytophthora infestans (Haas et al. 2009), Pectobacterium atrosepticum (Bell et al. 2004), and Dickeya spp. (Pritchard et al. 2013) genome sequencing. Comparative genomics of plant pathogens (Toth et al. 2006), including microarray comparative genomic hybridisation (Pritchard et al. 2009). Identification and classification of pathogen effectors and their targets (McLellan et al. 2013, McNally et al. 2012, Whisson et al. 2007, Haas et al. 2009) and other genomic features (Jupe et al. 2013, Jupe et al. 2012, Avrova et al. 2007, Kikuchi et al. 2007, Whisson et al. 2005, Bell et al. 2004). Diagnostic assays from rough draft genome sequences (Pritchard et al. 2012, Pritchard et al. 2013).
Oomycete and bacterial plant pathogens
- Much of my work is in support of the practical goal of reducing the impact of severe and financially significant crop diseases caused by oomycete and bacterial plant pathogens, such as Phytophthora infestans and Dickeya species. In order to understand the relationship between our models and the outcome of infection, we need to appreciate both the biological and the mathematical details of the problem. Oomycete effector proteins (Birch et al. 2009, Birch et al. 2006, Armstrong et al. 2005), and interactions with plant defences (Gilroy et al. 2007). Microarray design and analysis of gene expression profiles in bacterial plant pathogens (McNally et al. 2012, Antunez-Lamas et al. 2009, Ravirala et al. 2007). Persistence of human pathogenic bacteria on plants (Holden et al. 2008).
Computational Biology and Bioinformatics
- Bioinformatics and mathematics are the tools that I use to study and make sense of biological sequences and other data. I am interested in visualisation tools for large datasets, and a collaboration in this area with Ian Toth, Michel Perombelon, and Prof. Elaine Shemilt of the Duncan of Jordanstone College of Art and Design resulted in exhibitions in Dundee and Singapore. I have also contributed code to open source bioinformatics projects, including Biopython. Visualisation of comparative genomic data (Pritchard et al. 2006). Galaxy (Cock et al. 2013). Tablet (Milne et al. 2013). Directed evolution and error-prone PCR (Pritchard et al. 2005). Protein sequence-structure-function analysis, including covariation analysis (Pritchard et al. 2003, Pritchard et al. 2001, Pritchard and Dufton 2000, Pritchard and Dufton, 1999)
Collaborations
- Plant pathogen research is a multidisciplinary effort, and I collaborate with a number of researchers in a range of fields, in the UK and internationally.
Publications
Journals
- Cooke, D. E. L.; Cock, P. J. A.; Thorpe, P.; Pritchard, L. (2023) THAPBI PICT a fast, cautious, and accurate metabarcoding analysis pipeline, PeerJ, 11, Art. e15648
- McLellan, H.; Harvey, S.E.; Steinbrenner, J.; Armstrong, M.R.; He, Q.; Clewes, R.; Pritchard, L.; Wang, W.; Wang, S.; Nussbaumer, T.; Dohai, B.; Luo, Q.; Kumari, P.; Roberts, A.; Boevink, P.C.; Neumann, C.; Champouret, N.; Hein, I.; Falter-Braun, P.; Beynon, J.; Denby, K.; Birch, P.R.J. (2022) Exploiting breakdown in nonhost effector-target interactions to boost host disease resistance, Proceedings of the National Academy of Sciences USA, 119(35), Art. E2114064119
- Green, S.; Cooke, D.E.L.; Dunn, M.; Barwell, L.; Purse, B.; Chapman, D.S.; Valatin, G.; Schlenzig, A.; Barbrook, J.; Pettitt, T.; Price, C.; Pérez-Sierra, A.; Frederickson-Matika, D.; Pritchard, L.; Thorpe, P.; Cock, P.J.A.; Randall, E.; Keillor, B.; Marzano, M. (2021) PHYTO-THREATS: Addressing Threats to UK Forests and Woodlands from Phytophthora; Identifying Risks of Spread in Trade and Methods for Mitigation, Forests, 12(12), Art. 1617
- Pasanen, M.; Waleron, M.; Schott, T.; Cleenwerck, I.; Misztak, A.; Waleron, K.; Pritchard, L.; Bakr, R.; Degefu, Y.; van der Wolf, J.; Vandamme, P.; Pirhonen, M. (2020) Pectobacterium parvum sp. nov., having a Salmonella SPI-1-like Type III secretion system and low virulence., International Journal of Systematic and Evolutionary Microbiology, 70, 2440-2448.
- Holmes, A.; Pritchard, L.; Hedley, P.; Morris, J.; McAteer, S.P.; Gally, D.L.; Holden, N.J. (2020) A high-throughput genomic screen identifies a role for the plasmid-borne type II secretion system of Escherichia coli O157:H7 (Sakai) in plant-microbe interactions., Genomics, 112, 4242-4253.
- Holmes, A.; Pritchard, L.; Hedley, P.; Morris, J.; McAteer, S.P.; Gally, D.L.; Holden, N.J. (2020) Dataset of Escherichia coli O157:H7 genes enriched in adherence to spinach root tissue., Data in Brief, 31, Article No. 105769.
- Green, S.; Riddell, C.E.; Frederickson-Matika, D.; Armstrong, A.C.; Elliott, M.; Forster, J.; Hedley, P.E.; Morris, J.; Thorpe, P.; Cooke, D.E.L.; Sharp, P.M.; Pritchard, L. (2020) Diversity of woody-host infecting Phytophthora species in public parks and botanic gardens as revealed by metabarcoding, and opportunities for mitigation through best practice., Sibbaldia, 18, 67-88.
- Riddell, C.E.; Frederickson-Matika, D.; Armstrong, A.C.; Elliot, M.; Forster, J.; Hedley, P.E.; Morris, J.; Thorpe, P.; Cooke, D.E.L.; Pritchard, L.; Sharp, P.M.; Green, S. (2019) Metabarcoding reveals a high diversity of woody host-associated Phytophthora spp. in soils at public gardens and amenity woodlands in Britain., PeerJ, 7, Article No. e6931.
- Somorin, Y.M.; Vollmerhausen, T.; Waters, N.; Pritchard, L.; Abram, F.; Brennan, F.; O’Byrne, C. (2018) Absence of Curli in soil-persistent Escherichia coli is mediated by a C-di-GMP signaling defect and suggests evidence of biofilm-independent niche specialization., Frontiers in Microbiology, 9 Article No. 1340.
- Waters, N.R.; Abram, F.; Brennan, F.; Holmes, A.; Pritchard, L. (2018) riboSeed: leveraging prokaryotic genomic architecture to assemble across ribosomal regions., Nucleic Acids Research, 46. Article No. e68.
- Joynson, R.; Pritchard, L.; Osemwekha, E.; Ferry, N. (2017) Metagenomic analysis of the gut microbiome of the common black slug arion ater in search of novel lignocellulose degrading enzymes., Frontiers in Microbiology, 8, Article No. 2181.
- Waters, N.R.; Abram, F.; Brennan, F.; Holmes, A.; Pritchard, L. (2017) riboSeed: leveraging prokaryotic genomic architecture to assemble across ribosomal regions., bioRxiv, Article No. 159798.
- Pritchard, L.; Glover, R.H.; Elphinstone, J.G.; Toth, I.K. (2016) Genomics and taxonomy in diagnostics for food security: soft-rotting enterobacterial plant pathogens., Analytical Methods, 8, 12-24.
- Toth, I.K.; Humphris, S.; Campbell, E.; Pritchard, L. (2015) Why genomics research on Pectobacterium and Dickeya makes a difference., American Journal of Potato Research, 92, 218-222.
- Parkinson, N.; Pritchard, L.; Bryant, R.; Toth, I.K.; Elphinstone, J. (2015) Epidemiology of Dickeya dianthicola and Dickeya solani in ornamental hosts and potato studied using variable number tandem repeat analysis., European Journal of Plant Pathology, 141, 63-70.
- Pritchard, L.; Birch, P.R.J. (2014) The zigzag model of plant-microbe interactions: is it time to move on?, Molecular Plant Pathology, 15, 865-870.
- van der Wolf, J.M.; Nijhuis, E.H.; Kowalewska, M.J.; Saddler, G.S.; Parkinson, N.; Elphinstone, J.G.; Pritchard, L.; Toth, I.K.; Lojkowska, E.; Potrykus, M.; Waleron, M.; de Vos, P.; Cleenwerck, I.; Pirhonen, M.; Garlant, L.; Helias, V.; Pothier, J.F.; Pfluger, V.; Duffy, B.; Tsror, L.; Manulis, S. (2014) Dickeya solani sp. nov., a pectinolytic plant pathogenic bacterium isolated from potato (Solanum tuberosum)., International Journal of Systematic and Evolutionary Microbiology, 64, 768-774.
- Jupe, F.; Witek, K.; Verweij, W.; Sliwka, J.; Pritchard, L.; Etherington, G.J.; Maclean, D.; Cock, P.J.; Leggett, R.M.; Bryan, G.J.; Cardle, L.; Hein, I.; Jones, J.D.G. (2013) Resistance gene enrichment sequencing (RenSeq) enables reannotation of the NB-LRR gene family from sequenced plant genomes and rapid mapping of resistance loci in segregating populations., Plant Journal, 76, 530-544.
- Pritchard, L.; Humphris, S.; Saddler, G.S.; Elphinstone, J.G.; Pirhonen, M.; Toth, I.K. (2013) Draft Genome Sequences of 17 isolates of the plant pathogenic bacterium Dickeya., Genome Announcements, 1, Article No. e00978-13.
- McLellan, H.; Boevink, P.C.; Armstrong, M.R.; Pritchard, L.; Gomez, S.; Morales, J.; Whisson, S.C.; Beynon, J.L.; Birch, P.R.J. (2013) An RxLR effector from Phytophthora infestans prevents re-localisation of two plant NAC transcription factors from the endoplasmic reticulum to the nucleus., PLoS Pathogens, 9, Article No. e1003670.
- Cock, P.J.A.; Gruning, B.A.; Paszkiewicz, K.; Pritchard, L. (2013) Galaxy tools and workflows for sequence analysis with applications in molecular plant pathology., Peer J, 1, Article No. e167.
- Pritchard, L.; Humphris, S.; Baeyen, S.; Maes, M.; Van Vaerenbergh, J.; Elphinstone, J.; Saddler, G.; Toth, I.K. (2013) Draft genome sequences of four Dickeya dianthicola and four Dickeya solani strains., Genome Announcements, 1, Article No. e0087-12.
- Pritchard, L.; Humphris, S.; Saddler, G.S.; Parkinson, N.M.; Bertrand, V.; Elphinstone, J.G.; Toth, I.K. (2013) Detection of phytopathogens of the genus Dickeya using a PCR primer prediction pipeline for draft bacterial genome sequences., Plant Pathology, 62, 587-596.
- Milne, I.; Stephen, G.; Bayer, M.M.; Cock, P.J.A.; Pritchard, L.; Cardle, L.; Shaw, P.; Marshall, D.F. (2013) Using Tablet for visual exploration of second generation sequencing data., Briefings in Bioinformatics, 14, 193-202.
- Pritchard, L.; Holden, N.J.; Bielaszewska, M.; Karch, H.; Toth, I.K. (2012) Alignment-free design of highly discriminatory diagnostic primer sets for Escherichia coli O104:H4 outbreak strains., PLoS ONE, 7, Article No. e34498.
- Rio-Alvarez, I.; Rodriguez-Herva, J.J.; Cuartas-Lanza, R.; Toth, I.K.; Pritchard, L.; Rodriguez-Palenzuela, P.; Lopez-Solanilla, E. (2012) Genome-wide analysis of the response of Dickeya dadantii 3937 to plant antimicrobial peptides., Molecular Plant-Microbe Interactions, 25, 523-533.
- McNally, R.R.; Toth, I.K.; Cock, P.J.A.; Pritchard, L.; Hedley, P.E.; Morris, J.A.; Zhao, Y.F.; Sundin, G.W. (2012) Genetic characterization of the HrpL regulon of the fire blight pathogen Erwinia amylovora reveals novel virulence factors., Molecular Plant Pathology, 13, 160-173.
- Jupe, F.; Pritchard, L.; Etherington, G.; MacKenzie, K.; Cock, P.J.A.; Wright, F.; Sharma, S.K.; Bolser, D.; Bryan, G.J.; Jones, J.; Hein, I. (2012) Identification and localisation of the NB-LRR gene family within the potato genome., BMC Genomics,13, 1-14.
- Gilroy, E.M.; Breen, S.; Whisson, S.C.; Squires, J.; Hein, I.; Kaczmarek, M.; Turnbull, D.; Boevink, P.; Lokossou, A.; Cano, L.M.; Morales, J.; Avrova, A.O.; Pritchard, L.; Randall, E.; Lees, A.K.; Govers, F.; van West, P.; Kamoun, S.; Vleeshouwers, V.G.A.A.; Cooke, D.E.L.; Birch, P.R.J. (2011) Presence/absence, differential expression and sequence polmorphisms between PiAVR2 and PiAVR2-like in Phytophthora infestans determine virulence on R2 plants., New Phytologist, 191, 763-776.
- Pritchard, L.; Birch, P.R.J. (2011) A systems biology perspective on plant-microbe interactions: Biochemical and structural targets of pathogen effectors., Plant Science, 180, 584-603.
Books / chapters
- Humphris, S.N.; Cahill, G.; Elphinstone, J.G.; Kelly, R.; Parkinson, N.M.; Pritchard, L.; Toth, I.K.; Saddler, G.S. (2015) Detection of the bacterial potato pathogens Pectobacterium and Dickeya spp using conventional and real time PCR., In: Lacomme, C. (ed.). Plant Pathology: Techniques and Protocols. (Methods in Molecular Biology, 1302). Humana Press, New York, 2nd edition, Chapter 1, pp1-16.
- Pritchard, L.; Broadhurst, D. (2014) On the statistics of identifying candidate pathogen effectors., In: Birch, P.R.J., Jones, J.T. & Bos, J.I.B. (eds.). Plant-Pathogen Interactions: Methods and Protocols. Methods in Molecular Biology, Volume 1127. Humana Press, New York, 2nd ed. Chapter 4, 53-65.
- Cock, P.; Pritchard, L. (2014) Galaxy as a platform for identifying candidate pathogen effectors., In: Birch, P.R.J., Jones, J.T. & Bos, J.I.B. (eds.). Plant-Pathogen Interactions: Methods and Protocols. Methods in Molecular Biology, Volume 1127. Humana Press, New York, 2nd ed. Chapter 1, 3-15.
- Holden, N.; Pritchard, L.; Toth, I.K.; Wright, K.M. (2013) Mechanism of plant colonisation by human pathogenic enterobacteria: an emphasis on the roots and rhizosphere., In: de Bruijn, F. (ed.). Molecular Microbial Ecology of the Rhizosphere. Wiley Blackwell, Hoboken, New Jersey, Volume 2, Chapter 117, pp1217-1226.
- Lin, K.; Husmeier, D.; Dondelinger, F.; Mayer, C.D.; Liu, H.; Pritchard, L.; Salmond, G.P.C.; Toth, I.K.; Birch, P.R.J. (2010) Reverse engineering gene regulatory networks related to quorum sensing in the plant pathogen Pectobacterium atrosepticum., In: Fenyo, D. (ed.). Computational Biology. Springer, New York, Chapter 17, pp253-281.
- Toth, I.K.; Pritchard, L.; Birch, P.R.J.; Liu, H. (2008) Genomics of the enterobacterial plant pathogens., In: Jackson, R.W. (ed.). Plant Pathogenic Bacteria: Genomics and Molecular Biology. Caister Academic Press, Norfolk, 163-174.
- Toth, I.K.; Moleleki, L.N.; Pritchard, L.; Liu, H.; Humphris, S.N.; Hyman, L.; Axelsen, G.W.; Brurberg, M.B.; Ravensdale, M.; Gilroy, E.M.; Birch, P.R.J. (2006) Erwiniae: genomics and the secret life of a plant pathogen., In: Bailey, M.J., Lilley, A.K., Timms-Wilson, T.M. & Spencer-Phillips, P.T.N. (eds.). Microbial Ecology of Aerial Plant Surfaces. CABI Publishing, Wallingford, pp191-201.
Technical / contract reports
- Avrova, A.O.; Birch, P.R.J.; Hein, I.; Jones, J.T.; Pritchard, L. (2010) Functional analysis of pathogen effectors: how to go from genomics to durable resistance., Annual Report of the Scottish Crop Research Institute for 2009, 39-41.
- Whisson, S.C.; Boevink, P.; Pritchard, L.; Avrova, A.O.; Morales, J.; Birch, P.R.J. (2006) Effector protein translocation in the Phytophthora infestans – potato infection., Annual Report of the Scottish Crop Research Institute for 2006, pp24-25.
- Toth, I.K.; Pritchard, L.; Holeva, M.C.; Hyman, L.J.; Bell, K.S.; Whisson, S.C.; Avrova, A.O.; Birch, P.R.J. (2004) New discoveries with Erwinia genomics., Annual Report of the Scottish Crop Research Institute for 2002/2003, p101.
Conference papers
- Green, S.; Cooke, D.E.L.; Frederickson-Matika, D.; Clark, B.; Randall, E.; Clark, M.; Pettit, T.; Dunn, M.; Schlenzig, A.; Pritchard, L.; Thorpe, P.; Cock, P.; Barbrook, J. (2019) Phytophthora communities in UK plant nurseries and links to management practice: opportunities for mitigation through accreditation., Presentation at the 9th Meeting of the IUFRO Working Party 7.02.09: Phytophthora in Forests and Natural Ecosystems, Sardinia 17-25 October 2019.
- Cooke, D.E.L.; Randall, E.; Clark, B.; Thorpe, P.; Cock, P.J.; Pritchard, L.; Pettitt, T.; Frederickson-Matika, D.; Green, K.R. (2019) Phytophthora eDNA barcoding for natural ecosystem surveillance., 20th Oomycete Molecular Genetics Network Annual Meeting, Scottish Association for Marine Science (SAMS), Oban, 10-12 July 2019. Presentation.
- Cooke, D.E.L.; Randall, E.; Clark, B.; Thorpe, P.; Pritchard, L.; Pettitt, T.; Frederickson-Matika, D.; Green, S. (2018) The validation of eDNA barcoding in the study of Phytophthora diversity for plant health testing and natural ecosystem surveillance., Presentation at The 6th International Oomycetes Workshop: Phytophthora, Pythium, Downy Mildews and Related Genera 2018, Boston, USA. 28 July 2018.
- Cooke, D.E.L.; Pritchard, L.; Thorpe, P.; Green, S.; Taylor, A. (2017) eDNA and plant pathogen metabarcoding., Presentation at SNH Sharing Good Practice, The Use of Technology to Gather Data about the Natural Environment, Battleby, Perth, UK, 7 June 2017.
- Cooke, D.E.L.; Prigigallo, M.I.; Schena, L.; Randall, E.; Squires, J.N.; Clark, B.; Thorpe, P.; Pritchard, L.; Studholme, D.J.; Boonham, N.; Henricot, B.; Green, S. (2017) Testing in situ water sampling and metabarcoding protocols to detect Phytophthora diversity for plant health testing and natural ecosystem surveillance., Presentation at the Eighth meeting of the International Union of Forest Research Organizations (IUFRO) Working Party S07.02.09. SaPa, Vietnam, 19-25 March 2017.
- Toth, I.K.; Saddler, G.; Cahill, G.; Elphinstone, J.; Wale, S.; Gibson-Poole, S.; Humphris, S.; Pritchard, L.; Campbell, E.; Watts, L. (2017) Developing an IPM toolbox for blackleg disease., European Association for Potato Research triennial conference, Versailles, Paris, France. 9-14 July 2017.
- Toth, I.K.; Humphris, S.; Pritchard, L.; Skelsey, P. (2014) Environmental spread of Pectobacterium and Dickeya: diagnostics to modelling., Euphresco Pectobacterium and Dickeya Workshop, Bern, Switzerland, 25 November 2014.
- Cooke, D.E.L.; Squires, J.N.; Randall, E.; Pritchard, L.; Birch, P.R.J. (2013) Tracking effector diversity in populations of Phytophthora infestans., COST-FA1208 Meeting on Pathogen-informed Strategies for Sustainable Broad-spectrum Crop Resistance, Birnam, 9-11 October 2013.
- Toth, I.K.; Pritchard, L.; Humphris, S.; Douglas, E.; Birch, P.R.J. (2013) Genomic approaches to research on Pectobacterium and Dickeya species., International Congress of Plant Pathology (ICPP), Beijing, China, 25 – 30 August 2013.
- Pritchard, L.; Humphris, S.; Campbell, E.; Elphinstone, J.; Saddler, G. (2013) The environment and pathogen detection: how genomics research on the bacterial plant pathogens Pectobacterium and Dickeya makes a difference to potato growers., 97th Annual Meeting of the Potato Association of America, Quebec City, Canada, 28 July – 1 August 2013.
- Toth, I.K.; Pritchard, L.; Humphris, S.; Campbell E.; Birch, P.R.J. (2013) Pathogenicity and resistance: how genomics research on the bacterial plant pathogens Pectobacterium and Dickeya makes a difference to potato growers., 97th Annual Meeting of the Potato Association of America, Quebec City, Canada, 28 July – 1 August 2013.
- Pritchard, L.; Toth, I.K. (2012) Dickeya genomics at JHI – latest progress., Euphresco ERA-NET on Dickeya, 5-6 November 2012.
- Toth, I.K.; Pritchard, L.; Humphris, S. (2012) Designing ‘D. solani’ diagnostics the genome way., Euphresco ERA-NET on Dickeya, 5-6 November 2012.
- Toth, I.K.; Holden, N.; Pritchard, L. (2012) Genomics research on Pectobacterium and Dickeya species: disease, ecology and diagnosis., Molecular Plant Microbe Interactions (MPMI) Conference, Kyoto, Japan, 27 July 2012.
- Toth, I.K.; Holden, N.; Pritchard, L. (2012) We only find what we look for: can enteric pathogens of animals live on and be spread by plants?, KNVM/NVMM Dutch Microbiology Society, Papendal, the Netherlands, 17 April 2012.
- Humphris, S.; Campbell, E.; Pritchard, L.; Elphinstone, J.; Parkinson, N.; Saddler, G.; Toth, I.K. (2011) Dickeya solani in the environment., Euphresco Meeting on Dickeya, 7 November 2011.
- Pritchard, L.; Toth, I.K. (2011) How to sequence a bacterial genome., Euphresco Meeting on Dickeya, 7 November 2011.
- Toth, I.K.; Pritchard, L. (2011) Genomics leads to new discoveries and practical solutions to blackleg disease control., European Association for Potato Research (EAPR) Conference, Oulu, Finland, 24-29 July 2011.
- Toth, I.K.; Pritchard, L. (2011) Whole genome microarrays: quorum sensing and species-specific genomic islands in Pectobacterium atrosepticum., Southern African Society for Plant Pathology, Kruger National Park, South Africa, 23-26 January 2011.
- Whisson, S.C.; Gilroy, E.M.; Avrova, A.O.; Tian, Z.D.; Breen, S.; Armstrong MR.; Squires, J.; Vieeshouwers, V.; McLellan, H.; Seman, Z.; Kandel, K.; Boevink, P.C.; Pritchard, L.; Hein, I.; Cooke, D.E.L.; Birch, P.R.J.; (2011) Phytophthora infestans effectors in late blight disease development and exploitation for disease control., 18th Triennial Conference of the European Association for Potato Research, Oulu, Finland, 24-29 July 2011.
- Toth, I.K.; Liu, H.; Coulthurst, S.J.; Humphris, S.; Douglas, E.; Hedley, P.E.; Booth, C.; Ravensdale, M.; Burr, T.; Takle, G.; Bruberg, M.; Birch, P.R.J.; Salmond, G.P.C.; Francois, P.; Schrenzel, J.; Pritchard, L. (2010) Whole genome microarrays to investigate the potato pathogen Pectobacterium atrosepticum species-specific genomic islands and quorum sensing., International Conference on Plant Pathogenic Bacteria (ICPPB). Reunion, 7-11 June 2010.
- Toth, I.K.; Humphris, S.; Douglas, E.; Pritchard, L.; Birch, P.R.J.; Takle, G.; Brurberg, M.B.; (2010) Genomics uncovers a life on plants away from disease for the potato pathogen Pectobacterium atrosepticum., International Erwinia Workshop, Reunion, 5-6 June 2010.
- Toth, I.K.; Birch, P.R.J.; Pritchard, L.; Liu, H.; Hedley, P.E.; Humphris, S.; Douglas, E.; Gilroy, E.M.; Moleleki, L.N.; Ravensdale, M.; Hardy, D.; Mayer, C.; Husmeier, D.; Lin, K. (2010) From bully to master tactician: a genomics approach reveals unexpected traits in the life of the bacterial plant pathogen Pectobacterium., IFR Seminar Series. Institute of Food Research, 4 March 2010.
- Toth, I.K.; Birch, P.R.J.; Pritchard, L.; Humphris, S.N.; Douglas, E.; Gilroy, E.M.; Morris, J.; Hedley, P.E. (2010) Using genomics approaches to investigate the life of the bacterial potato pathogen Pectobacterium atrosepticum., COST 872 Nemagenics. Exploiting genomics to understand plant-nematode interactions, 4th Annual Meeting. Lisbon, Portugal, 24-27 May 2010.
- McLellan, H.; Tian, Z.D.; Avrova, A.O.; Gilroy, E.M.; Pritchard, L.; Whisson, S.C.; Birch, P.R.J. (2010) Identification of RXLR effectors essential for virulence in Phytophthora infestans., Oomycete Molecular Genetics Network Congress, Toulouse, France, 6-8 June 2010.
- Breen, S.; Gilroy, E.M.; Armstrong, M.R.; Morales, J.G.; Hein, I.; Douglas, E.; Boevink, P.; McLellan, H.; Randall, E.; Tian, Z.D.; Avrova, A.O.; Pritchard, L.; Lokossou, A.A.; Govers, F.; van der Vossen, E.A.G.; Vleeshouwers, V.G.A.A.; Brunner, F.; Whisson, S.C.; Birch, P.R.J. (2010) Avr2, an RXLR effector from Phytophthora infestans., Oomycete Molecular Genetics Network Congress, Toulouse, France, 6-8 June 2010.
- Armstrong, M.R.; Boevink, P.; Bukharova, T.; McLellan, H.; Ramos, M.; Gilroy, E.M.; Pritchard, L.; Whisson, S.C.; Beynon, J.; Birch, P.R.J. (2010) Identifying candidate host ‘targets’ of Phytophthora infestans translocated RXLR proteins., Oomycete Molecular Genetics Network Congress, Toulouse, France, 6-8 June 2010.
- Gilroy, E.M.; Hein, I.; McLellan, H.; Breen, S.; Engelhardt, S.; Tian, Z.D.; Seman, Z.A.; Pritchard, L.; Armstrong, M.R.; Randall, E.; Avrova, A.O.; Cooke, D.E.L.; Lees, A.K.; Vleeshouwers, V.G.A.A.; van West, P.; Whisson, S.C.; Birch, P.R.J. (2010) Using knowledge of RXLR effectors to seek durable resistance., Oomycete Molecular Genetics Network Congress, Toulouse, France, 6-8 June 2010.
- Gilroy, E.M.; Breen, S.; Hein, I.; Tian, Z.D.; Armstrong, M.R.; Douglas, E.; Lokossou, A.A.; Boevink, P.; McLellan, H.; Randall, E.; Morales, J.G.; Avrova, A.O.; Pritchard, L.; van der Vossen, E.A.G.; Whisson, S.C.; Birch, P.R.J. (2009) Amino acid polymorphisms upstream of the RXLR motif in Phytophthora infestans effector Avr2 condition R gene recognition., The Fungal Cell, British Mycological Society Meeting, Westpark Conference Centre, Dundee, 1-4 September 2009.
- Hein, I.; Gilroy, E.M.; Whisson, S.C.; Pritchard, L.; Bryan, G.J.; Birch, P.R.J. (2009) Exploiting the Phytophthora infestans genome to determine targets for sustainable potato protection., XIV MPMI Conference, Montreal, Canada, 19-23 July 2009.
Conference posters / abstracts
- Pritchard, P.; Cock, P.J.A.; Thorpe, P.; Randall, E.; Green, S.; Cooke, D.E.L. (2019) Metabarcoding diagnostics of Phytophthora species in environmental samples., XVIII International Congress on Molecular Plant-Microbe Interactions, Glasgow, UK, 14-18 July 2019. Abstract.
- Green, S.; Cooke, D.E.L.; Frederickson-Matika, D.; Clark, B.; Randall, E.; Thorpe, P.; Pritchard, L.; Cock, P.; Pettitt, T.; Schlenzig, A.; Barbrook, J. (2019) PHYTO-THREATS: An analysis of Phytophthora communities in plant nurseries., Proceedings of XXV IUFRO World Congress 2019: Forest Research and Cooperation for Sustainable Development, Curitiba, Brazil 29 September – 5 October 2019. Pesquisa Forestal Brasileira – Brazilian Journal of Forestry Research, Colombo, v. 39, e201902043. Abstract.
- Toth, I.K.; Campbell, E.; Cahill, G.; Elphinstone, J.; Humphris, S.; Saddler, G.S.; Wale, S.; Watts, L.; Pritchard, L.; Harper, G. (2018) Population studies of Pectobacterium atrosepticum: How it’s shaping our view of seed-borne vs environmental sources of infection., Phytopathology, 108, S1.259. Abstract.
- Green, S.; Cooke, D.E.L.; Marzano, M.; Purse, B.; Sharp, P.; Chapman, D.; Schlenzig, A.; Barbrook, J.; Pettit, T.; Pérez-Sierra, A.; Henricot, B.; Frederickson-Matika, D.; Valatin, G.; Dunn, M.; Pritchard, L.; Thorpe, P.; Barwell, L.; Clark, M. (2017) PHYTO-THREATS: A multi-disciplinary approach to address global threats from Phytophthora species., International Union of Forest Research Organizations (IUFRO) 125th Anniversary Congress, Freiburg, Germany, 18-22 September 2017. (Poster)
- Pritchard, L.; Humphris, S.; Saddler, G.; Parkinson, N.; Bertrand, V.; Elphinstone, J.; Toth, I. (2014) A new method of generating diagnostic primers from draft bacterial genome sequences., European Food Safety Authority (EFSA), Parma, 1-3 April 2014.
- Brennan, F.P.; Pritchard, L.; Holden, N.M.; Abram, F. (2014) Exploring the genomic and phenotypic basis for E.coli naturalisation in soil., In: Cooperative of Zoonoses Experience and Expertise (CoZEE) Conference: The Role of High-throughput Sequencing in Surveillance, Diagnostics and Tracking Zoonotic Bacteria, The James Hutton Institute, Dundee, 11-12 November 2014.
- Pritchard, L.; Bayer, M.; Cock, P.; Flores, P.; Jones, S.; Milne, I.; Shaw, P.; Marshall, D. (2014) James Hutton Institute Bioinformatics Grouping., Data Science Research Day, University of Edinburgh, 12 September 2014.
- Pritchard, L.; Toth, I.K.; Humphris, S. (2013) Dickeya comparative metabolism., 14th International Conference on Systems Biology, Copenhagen, Denmark, 29 August – 4 September 2013.
- Hein, I.; Gilroy, E.; Hornyik, C.; Bryan, G.; Milne, I.; Toth, I.K.; Ducreux, L.; Torrance, L.; Milne, L.; Cock, P.; Pritchard, L.; Sharma, K.; MacFarlane, S.; Zhang, R.; Hedley, P.; Jones, J.; Birch, P.; Taylor, M.; Dale, F.; McNaughton, I.; Wright, J.; Prashar, A.; Blok, V.; Carnegie, P.; Chapman, S. (2013) Utilising the potato genome., Potatoes in Practice 2013, Balruddery Farm, Invergowrie, Dundee, 8 August 2013.
- Birch, P.R.J.; Boevink, P.C.; Gilroy, E.M.; Hein, I.; Pritchard, L.; Whisson, S.C. (2012) Effectors from the potato late blight pathogen: their roles in suppressing or triggering the plant immune system., EPS Autumn-school, Wageningen, 6 March 2012.
- Birch, P.R.J.; Boevink, P.C.; Gilroy, E.M.; Hein, I.; Pritchard, L.; Randall, E.; Whisson, S.C. (2011) Effectors from the potato late blight pathogen: their roles in suppressing or triggering the plant immune system., British Mycological Society Meeting, Exeter, September 2011.
- Gilroy, E.M.; Breen, S.; Morales, J.G.; Lokossou, A.A.; Ramos, B.; Armstrong, M.R.; Hein, I.; Boevink, P.; Pritchard, L.; van der Vossen, E.A.G.; Vleeshouwers, V.G.A.A.; Whisson, S.C.; Birch, P.R.J. (2009) Cloning and functional analysis of Phytophthora infestans RXLR effector, Avr2., 22nd New Phytologist Symposium on Effectors in Plant-Microbe Interactions, INRA Versailles Research Centre, Paris, France, 13-16 September 2009 (Poster).
- Armstrong, M.R.; Whisson, S.C.; Pritchard, L.; Bos, J.I.B.; Venter, E.; Avrova, A.O.; Rehmany, A.P.; Huang, S.; Kamoun, S.; Beynon, J.; Birch, P.R.J. (2005) An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognised in the host cell cytoplasm., Molecular Plant Microbe Interactions Conference, Merida, Mexico, 14-19 December 2005 (Poster).
